Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 12/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20898376 | 1.00 | POLB (0.43) | POLBFAAHLMNACHRM2ADRA2B | |
| SCHEMBL29631806 | 0.82 | NOS2 (0.51) | POLBFAAHLMNACHRM2ADRA2B | |
| SCHEMBL20900383 | 0.82 | NOS2 (0.51) | POLBFAAHLMNACHRM2ADRA2B | |
| SCHEMBL20898384 | 0.82 | NOS2 (0.51) | POLBFAAHLMNACHRM2ADRA2B | |
| SCHEMBL9531338 | 0.81 | BCHE (0.49) | POLBDRD2 | |
| SCHEMBL28850336 | 0.81 | FAAH (0.51) | POLBFAAHLMNACHRM2ADRA2B | |
| SCHEMBL9533489 | 0.81 | BCHE (0.52) | LMNACHRM2ADRA2BSLC6A2SLC6A4 | |
| SCHEMBL9532009 | 0.80 | BCHE (0.51) | LMNACHRM2ADRA2BSLC6A2SLC6A4 | |
| SCHEMBL13233182 | 0.80 | BCHE (0.51) | LMNACHRM2ADRA2BSLC6A2SLC6A4 | |
| SCHEMBL28097062 | 0.80 | POLB (0.46) | POLBFAAHLMNACHRM2ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146462-A | The synthetic method of 4-[(S)-(4-chlorphenyl)-2-pyridinyl methoxy]-piperidino isopropyl isobutyrate | 重庆华邦胜凯制药有限公司 | 2016-11-23 | — | — | CN | disclosed |