Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 14/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28850271 | 0.90 | FAAH (0.50) | FAAHPOLBKCNH2CYP2C19LMNA | |
| Phenylalanine SCHEMBL5154392 | 0.89 | FAAH (0.49) | FAAHPOLBKCNH2CYP2C19LMNA | |
| SCHEMBL29631806 | 0.88 | NOS2 (0.51) | FAAHPOLBKCNH2CYP2C19LMNA | |
| SCHEMBL20900383 | 0.88 | NOS2 (0.51) | FAAHPOLBKCNH2CYP2C19LMNA | |
| SCHEMBL20898384 | 0.88 | NOS2 (0.51) | FAAHPOLBKCNH2CYP2C19LMNA | |
| SCHEMBL28093862 | 0.87 | GPR119 (0.51) | FAAHPOLBKCNH2LMNACHRM2 | |
| SCHEMBL28093861 | 0.87 | GPR119 (0.51) | FAAHPOLBKCNH2LMNACHRM2 | |
| SCHEMBL14198313 | 0.85 | CYP2D6 (0.57) | FAAHKCNH2CYP2C19LMNACHRM2 | |
| SCHEMBL14367742 | 0.83 | BCHE (0.52) | FAAHKCNH2LMNACHRM2ADRA2B | |
| SCHEMBL9532187 | 0.83 | BCHE (0.52) | FAAHKCNH2LMNACHRM2ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805302-B | Preparation method of 4- [ (4-chlorophenyl) -2-pyridylmethoxy ] -1-piperidine carboxylic ester | 北京联本医药化学技术有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-114805302-A | Preparation method of 4- [ (4-chlorphenyl) -2-pyridylmethoxy ] -1-piperidine carboxylate | 北京联本医药化学技术有限公司 | 2022-07-29 | — | — | CN | disclosed |