Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12458540 | 0.88 | SIGMAR1 (0.50) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8734162 | 0.86 | SIGMAR1 (0.46) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12788164 | 0.85 | TRPA1 (0.47) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11991409 | 0.85 | TRPA1 (0.47) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28087864 | 0.79 | THRB (0.40) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL358968 | 0.76 | SIGMAR1 (0.50) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12534489 | 0.76 | SIGMAR1 (0.50) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8240630 | 0.76 | SIGMAR1 (0.50) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2355328 | 0.76 | SIGMAR1 (0.50) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| Ammonia Solution, Strong SCHEMBL6014633 | 0.75 | SIGMAR1 (0.48) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110016097-A | A kind of low leachable, low melting point, Narrow Molecular Weight Distribution, ethylene-propylene random copolymer of thermal oxidation stability and its preparation method and application | 中国石油化工股份有限公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-109694420-A | Catalyst system and pre-polymerized catalyst and olefine polymerizing process for olefinic polymerization | 中国石油化工股份有限公司 | 2019-04-30 | — | — | CN | disclosed |
| CN-109694426-A | A kind of polypropylene and preparation method thereof | 中国石油化工股份有限公司 | 2019-04-30 | — | — | CN | disclosed |
| CN-109422834-A | A kind of low VOC, high just high flow polypropylene and preparation method thereof | 中国石油化工股份有限公司 | 2019-03-05 | — | — | CN | disclosed |
| CN-109422958-A | A kind of high flowing high-rigidity high-ductility polyolefin composition and preparation method thereof | 中国石油化工股份有限公司 | 2019-03-05 | — | — | CN | disclosed |
| CN-109422959-A | A kind of impact polypropylene composition and preparation method thereof | 中国石油化工股份有限公司 | 2019-03-05 | — | — | CN | disclosed |
| CN-104974285-B | A kind of polypropylene catalyst method for preparing ingredients thereof and catalyst | 中国石油化工股份有限公司 | 2017-08-22 | — | — | CN | disclosed |
| CN-104974286-B | Catalytic component and catalyst for propylene polymerization | 中国石油化工股份有限公司 | 2017-08-22 | — | — | CN | disclosed |
| CN-105940019-A | CATALYST SYSTEM FOR POLYMERIZATION OF AN OLEFIN | 沙特基础工业公司 | 2016-09-14 | — | — | CN | disclosed |
| CN-105940018-A | Procatalyst for polymerization of olefins | 沙特基础工业公司 | 2016-09-14 | — | — | CN | disclosed |
| CN-105940021-A | Catalyst system for olefin polymerization | 沙特基础工业公司 | 2016-09-14 | — | — | CN | disclosed |
| CN-105934449-A | Catalyst system for polymerization of olefin | 沙特基础工业公司 | 2016-09-07 | — | — | CN | disclosed |