Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | LAP3 | P28838 | 1/20 | 0.42 |
| ▸ | SCN4A | P35499 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11991409 | 0.90 | TRPA1 (0.47) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL12788164 | 0.90 | TRPA1 (0.47) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL28087738 | 0.86 | SIGMAR1 (0.44) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL28087864 | 0.83 | THRB (0.40) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL18489459 | 0.82 | SIGMAR1 (0.46) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL12459378 | 0.82 | SIGMAR1 (0.46) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL358968 | 0.80 | SIGMAR1 (0.50) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL2355328 | 0.80 | SIGMAR1 (0.50) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL8240630 | 0.80 | SIGMAR1 (0.50) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL985724 | 0.79 | TRPA1 (0.37) | SIGMAR1TAAR1SLC6A2MAOASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1228928-A | — | — | None | — | — | JP | disclosed |
| EP-0546573-B1 | Process for the preparation of stabilized polyolefins and products obtained therefrom | MONTELL NORTH AMERICA INC (US) | 1998-03-11 | — | — | EP | disclosed |
| EP-0361494-B1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC (US) | 1996-02-07 | — | — | EP | disclosed |
| EP-0434082-B1 | Components and catalysts for the polymerization of olefins | HIMONT INC (US) | 1995-10-25 | — | — | EP | disclosed |
| EP-0362705-B1 | Catalysts for the polymerization of olefins | HIMONT INC (US) | 1995-01-11 | — | — | EP | disclosed |
| US-5278210-A | Process for the preparation of stabilized polyolefins and products obtained therefrom | HIMONT INCORPORATED (US) | 1994-01-11 | — | — | US | disclosed |
| EP-0546573-A1 | Process for the preparation of stabilized polyolefins and products obtained therefrom | MONTELL NORTH AMERICA INC. (US) | 1993-06-16 | — | — | EP | disclosed |
| US-5122492-A | Magnesium dihalide, titanium halide or halogen alcoholate on porous metal oxide | HIMONT INCORPORATED (US) | 1992-06-16 | — | — | US | disclosed |
| CN-1015062-B | COMPONENTS AND CATALYSTS FOR POLYMERIZATION OF OLEFINS | HIMONT INC (US) | 1991-12-11 | — | — | CN | disclosed |
| CN-1052681-A | The catalyst component of olefinic polymerization and catalyzer | HIMONT INC (US) | 1991-07-03 | — | — | CN | disclosed |
| EP-0434082-A2 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1991-06-26 | — | — | EP | disclosed |
| US-4978648-A | Alkyl-aluminum, diether, magnesium dichloride, titanium halide components; propylene polymerization | HIMONT INCORPORATED (US) | 1990-12-18 | — | — | US | disclosed |
| US-4971937-A | COORDINATION CATALYSTS OF TITANIUM HALIDES, MAGNESIUM HALIDES AND DI OR POLYETHER COMPOUNDS | HIMONT INCORPORATED (US) | 1990-11-20 | — | — | US | disclosed |
| CN-1042547-A | Olefinic polymerization composition and catalyzer | HIMONT INC (US) | 1990-05-30 | — | — | CN | disclosed |
| EP-0362705-A2 | Catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1990-04-11 | — | — | EP | disclosed |
| EP-0361494-A2 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1990-04-04 | — | — | EP | disclosed |
| JP-H01228928-A | LIGNANS AND ANTITUMOR AGENT CONTAINING LIGNANS AS ACTIVE INGREDIENT | TSUMURA & CO | 1989-09-12 | — | — | JP | disclosed |