Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NRP1 | O14786 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | MMP9 | P14780 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | F13A1 | P00488 | 1/20 | 0.36 |
| ▸ | TGM1 | P22735 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2808807 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TSHRNRP1MMP2MMP9 | |
| SCHEMBL13128306 | 0.92 | L3MBTL1 (0.42) | ALDH1A1TSHRMMP2MMP9CA1 | |
| SCHEMBL2807798 | 0.85 | ALDH1A1 (0.33) | ALDH1A1TSHRNRP1 | |
| SCHEMBL2807794 | 0.85 | ALDH1A1 (0.33) | ALDH1A1TSHRNRP1 | |
| SCHEMBL2807797 | 0.85 | ALDH1A1 (0.33) | ALDH1A1TSHRNRP1 | |
| SCHEMBL2812796 | 0.84 | MMP2 (0.47) | NRP1MMP2MMP9CA1CA2 | |
| SCHEMBL2812800 | 0.84 | MMP2 (0.47) | NRP1MMP2MMP9CA1CA2 | |
| SCHEMBL25352953 | 0.83 | MMP2 (0.50) | ALDH1A1TSHRMMP2MMP9CA1 | |
| SCHEMBL25352949 | 0.83 | MMP2 (0.50) | ALDH1A1TSHRMMP2MMP9CA1 | |
| SCHEMBL25354041 | 0.82 | MMP2 (0.46) | ALDH1A1TSHRNRP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240638-A1 | Organic Compounds and their uses | NOVARTIS AG (CH) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240638-A1 | Organic Compounds and their uses | OAT, HAVCR2, CYP3A43 | ALDH1A1 302/4885TSHR 4756/4885NRP1 3527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.