Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1355596 | 0.82 | ALDH1A1 (0.45) | KMT2AALDH1A1MEN1TSHRGAA | |
| SCHEMBL2902879 | 0.81 | HTT (0.46) | POLBKMT2AALDH1A1TSHRGAA | |
| SCHEMBL2900503 | 0.79 | KDM4E (0.48) | KMT2AALDH1A1MEN1TSHRGAA | |
| SCHEMBL1355211 | 0.79 | KMT2A (0.52) | KMT2AALDH1A1MEN1GAALMNA | |
| SCHEMBL2899236 | 0.78 | HTT (0.55) | POLBTDP1KMT2AALDH1A1MEN1 | |
| SCHEMBL2902630 | 0.77 | KMT2A (0.58) | POLBKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL29001789 | 0.77 | KMT2A (0.30) | KMT2A | |
| SCHEMBL2900768 | 0.76 | LMNA (0.49) | POLBTDP1ALDH1A1GAALMNA | |
| SCHEMBL2901269 | 0.76 | SMN1; SMN2 (0.48) | KMT2AALDH1A1MEN1GAALMNA | |
| SCHEMBL2894992 | 0.76 | SMN1; SMN2 (0.48) | KMT2AALDH1A1ALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105828820-A | Bromodomain inhibitors | 赛尔基因昆蒂赛尔研究公司 | 2016-08-03 | — | — | CN | disclosed |