Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15087903 | 0.91 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1MAPTPOLBHPGD | |
| SCHEMBL3105572 | 0.84 | CSNK2A1 (0.47) | L3MBTL1ALDH1A1MAPTPOLBHPGD | |
| SCHEMBL15197103 | 0.80 | TSHR (0.40) | L3MBTL1ALDH1A1POLBHPGDCYP2C9 | |
| SCHEMBL13861973 | 0.80 | L3MBTL1 (0.75) | L3MBTL1ALDH1A1MAPTPOLBHPGD | |
| SCHEMBL3324595 | 0.79 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1MAPTPOLBHPGD | |
| SCHEMBL2227815 | 0.79 | MAPT (0.50) | L3MBTL1ALDH1A1MAPTPOLBHPGD | |
| SCHEMBL22596995 | 0.79 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1MAPTPOLBHPGD | |
| SCHEMBL22964315 | 0.79 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1MAPTPOLBHPGD | |
| SCHEMBL8265598 | 0.79 | HPGD (0.50) | L3MBTL1ALDH1A1MAPTPOLBHPGD | |
| SCHEMBL27819584 | 0.79 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1MAPTPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105777756-B | Heteroaryl compound and its application in drug | 广东东阳光药业有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-105777756-A | Heteroaryl compound and application thereof in medicines | 广东东阳光药业有限公司 | 2016-07-20 | — | — | CN | disclosed |