Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15087903 | 0.81 | L3MBTL1 (0.45) | ALDH1A1LMNAMAPK1CYP2C19L3MBTL1 | |
| SCHEMBL3105572 | 0.80 | CSNK2A1 (0.47) | ALDH1A1LMNAMAPK1CYP2C19L3MBTL1 | |
| SCHEMBL28089646 | 0.79 | L3MBTL1 (0.50) | ALDH1A1LMNAMAPK1CYP2C19L3MBTL1 | |
| SCHEMBL16981203 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPK1CYP2C19L3MBTL1 | |
| SCHEMBL14937429 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPK1CYP2C19L3MBTL1 | |
| SCHEMBL29233797 | 0.79 | SLC6A4 (0.40) | ALDH1A1LMNACYP2C19L3MBTL1MAPT | |
| SCHEMBL4591980 | 0.76 | S1PR4 (0.47) | ALDH1A1LMNAMAPK1L3MBTL1NPSR1 | |
| SCHEMBL8955786 | 0.76 | ALDH1A1 (0.69) | ALDH1A1LMNAMAPK1CYP2C19L3MBTL1 | |
| SCHEMBL4574094 | 0.75 | MAP2K1 (0.39) | ALDH1A1LMNACYP2C19CYP1A2CYP2D6 | |
| SCHEMBL4684755 | 0.74 | TDP1 (0.56) | ALDH1A1CYP2C19L3MBTL1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120784-A1 | NOVEL HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120784-A1 | NOVEL HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | SCD, SCD5, ACSL6 | ALDH1A1 2012/4885LMNA 1764/4885MAPK1 3285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.