Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28089660 | 0.98 | ALDH1A1 (0.39) | ALDH1A1HPGDPKMMAPTSMN1; SMN2 | |
| SCHEMBL9632172 | 0.90 | EPHX2 (0.40) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL2237366 | 0.87 | LMNA (0.35) | ALDH1A1LMNAHCAR2 | |
| SCHEMBL5017623 | 0.84 | — | — | |
| SCHEMBL11318964 | 0.78 | MEN1 (0.40) | ALDH1A1HPGDPKMMAPTLMNA | |
| SCHEMBL5603217 | 0.78 | MEN1 (0.40) | ALDH1A1HPGDPKMMAPTLMNA | |
| SCHEMBL27338528 | 0.77 | ALDH1A1 (0.34) | ALDH1A1HPGDPKMMAPTHCAR2 | |
| SCHEMBL4788302 | 0.76 | ALDH1A1 (0.41) | ALDH1A1KDM4E | |
| SCHEMBL9750315 | 0.76 | HCAR2 (0.36) | ALDH1A1HPGDPKMMAPTHCAR2 | |
| SCHEMBL3722892 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0964028-B1 | Silica reinforced tire compositions containing triazoles | PIRELLI (IT) | 2003-10-29 | — | — | EP | claimed |