Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456849 | 0.79 | ERCC5 (0.47) | HSD17B1ERCC5FEN1ALOX5FLT1 | |
| SCHEMBL458039 | 0.79 | HSD17B1 (0.41) | HSD17B1ERCC5FEN1ALOX5FLT1 | |
| SCHEMBL456265 | 0.75 | ALDH1A1 (0.43) | CHRNA7RAB9A | |
| SCHEMBL13273703 | 0.75 | SHMT1 (0.38) | HSD17B1ERCC5FEN1FLT1FLT4 | |
| Acetic Acid SCHEMBL452191 | 0.73 | HSD17B1 (0.41) | HSD17B1ERCC5FEN1ALOX5GRIA2 | |
| SCHEMBL12603775 | 0.72 | AHR (0.50) | HSD17B1ERCC5FEN1ALOX5CNR1 | |
| SCHEMBL19847782 | 0.71 | AOC3 (0.36) | HSD17B1ERCC5FEN1FLT1FLT4 | |
| SCHEMBL559918 | 0.71 | ALDH1A1 (0.41) | ALOX5AOC3NPC1RAB9AIKBKB | |
| SCHEMBL12603786 | 0.71 | ALOX5 (0.41) | HSD17B1ERCC5FEN1ALOX5 | |
| SCHEMBL560893 | 0.70 | ALOX5 (0.41) | HSD17B1ERCC5FEN1ALOX5FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104277004-B | Prepare method and its intermediate of pyridazinone compound | 住友化学株式会社 | 2016-08-24 | — | — | CN | disclosed |