Benzophenone

Benzophenone

SCHEMBL28090168

CC(C)(C)c1cc(-n2nc3ccccc3n2)c(O)c(C(C)(C)C)c1.O=C(c1ccccc1)c1ccccc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.44
PTGS2 P35354 4/20 0.44
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
POLB P06746 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
TSHR P16473 1/20 0.40
CYP2C19 P33261 1/20 0.40
ALDH1A1 P00352 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
LMNA P02545 1/20 0.38
F2R P25116 1/20 0.38
VNN1 O95497 1/20 0.37
TNFRSF1A P19438 1/20 0.37
PPARG P37231 1/20 0.37
PPARA Q07869 1/20 0.37
PTGS1 P23219 2/20 0.36
SRD5A2 P31213 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31367920 0.90 PTGS2 (0.44) ALOX5PTGS2NPC1RAB9APOLB
SCHEMBL29350736 0.90 NPC1 (0.49) ALOX5PTGS2NPC1RAB9APOLB
SCHEMBL29708 0.90 NPC1 (0.49) ALOX5PTGS2NPC1RAB9APOLB
SCHEMBL1263980 0.86 NPC1 (0.42) ALOX5PTGS2NPC1RAB9APOLB
SCHEMBL27170340 0.85 NPC1 (0.43) ALOX5PTGS2NPC1RAB9APOLB
SCHEMBL28388612 0.85 NPC1 (0.43) ALOX5PTGS2NPC1RAB9APOLB
Oxybenzone SCHEMBL28079005 0.85 LMNA (0.56) NPC1RAB9APOLBCYP1A2CYP3A4
SCHEMBL1547141 0.83 RXRA (0.40) ALOX5PTGS2LMNASRD5A2
SCHEMBL5510301 0.83 NPC1 (0.41) ALOX5PTGS2NPC1RAB9APOLB
SCHEMBL7198524 0.82 NPC1 (0.52) ALOX5PTGS2NPC1RAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106019446-A OPTICAL UNIT AND ORGANIC LIGHT EMITTING DISPLAY INCLUDING THE SAME 三星显示有限公司 2016-10-12 CN disclosed
CN-103764777-B Contact adhesive LG化学株式会社 2016-08-17 CN disclosed