Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | RPA1 | P27694 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28090836 | 0.85 | HDAC1 (0.51) | ALDH1A1MEN1KMT2AHDAC1ADORA2A | |
| SCHEMBL28090835 | 0.85 | HTT (0.47) | HTTMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL28090518 | 0.77 | MAPT (0.54) | SMN1; SMN2HTTMAPTALDH1A1MEN1 | |
| SCHEMBL28090831 | 0.76 | MAPK14 (0.52) | MAPTALDH1A1MEN1KMT2AHDAC1 | |
| SCHEMBL28090668 | 0.76 | KMT2A (0.39) | SMN1; SMN2HTTMAPTALDH1A1MEN1 | |
| SCHEMBL28090523 | 0.76 | MAPT (0.44) | SMN1; SMN2HTTMAPTALDH1A1MEN1 | |
| SCHEMBL28090834 | 0.76 | HDAC1 (0.49) | ALDH1A1MEN1KMT2AHDAC1ADORA2A | |
| SCHEMBL2497315 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2HTTMAPTALDH1A1MEN1 | |
| SCHEMBL28090559 | 0.73 | MAPK14 (0.55) | SMN1; SMN2HTTMAPTALDH1A1MEN1 | |
| SCHEMBL28278292 | 0.73 | GABRA1 (0.45) | SMN1; SMN2HTTMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187923-A | 2 aryl 4 aroyl triazole compounds and application thereof | 沈阳药科大学 | 2016-12-07 | — | — | CN | disclosed |