Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28090523 | 0.78 | MAPT (0.44) | KMT2AKDM4EMEN1LMNAHTT | |
| SCHEMBL15577164 | 0.75 | RPA1 (0.49) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5591866 | 0.70 | HPGDS (0.69) | KMT2AKDM4EMEN1LMNAHTT | |
| SCHEMBL23354755 | 0.68 | GABRA2 (0.54) | KMT2AKDM4ELMNARAB9AALDH1A1 | |
| SCHEMBL23657627 | 0.67 | NPSR1 (0.54) | KMT2AKDM4EMEN1LMNAHTT | |
| SCHEMBL3771410 | 0.67 | HRH4 (0.51) | KMT2AKDM4EMEN1LMNAHTT | |
| SCHEMBL28090836 | 0.66 | HDAC1 (0.51) | KMT2AKDM4EMEN1RAB9AALDH1A1 | |
| SCHEMBL182010 | 0.65 | CES2 (0.71) | KMT2AKDM4EMEN1LMNAHTT | |
| SCHEMBL29172948 | 0.65 | KMT2A (0.45) | KMT2AKDM4EMEN1LMNAHTT | |
| SCHEMBL3226787 | 0.65 | MAPT (0.82) | KMT2AKDM4EMEN1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732050-B2 | Modulators of sperm hypermotility and uses thereof | HYDRA BIOSCIENCES, INC. (US) | 2017-08-15 | — | — | US | disclosed |
| US-20150335622-A1 | MODULATORS OF SPERM HYPERMOTILITY AND USES THEREOF | HYDRA BIOSCIENCES, INC. (US) | 2015-11-26 | — | — | US | disclosed |
| US-20130123310-A1 | MODULATORS OF SPERM HYPERMOBILITY AND USES THEREOF | HYDRA BIOSCIENCES, INC. (US) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123310-A1 | MODULATORS OF SPERM HYPERMOBILITY AND USES THEREOF | CATSPER1, SPAG5, NASP | KMT2A 1636/4885KDM4E 1062/4885MEN1 2188/4885 |
| US-20150335622-A1 | MODULATORS OF SPERM HYPERMOTILITY AND USES THEREOF | CATSPER1, SPAG5, ITPR3 | KMT2A 1670/4885KDM4E 1219/4885MEN1 2147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.