Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28090546 | 0.80 | CYP11B1 (0.48) | CYP19A1CYP11B1CYP11B2FGFR1CYP3A4 | |
| SCHEMBL9717769 | 0.74 | ALDH1A1 (0.58) | FGFR1ALDH1A1LMNATSHRTDP1 | |
| SCHEMBL18171689 | 0.73 | CYP19A1 (0.50) | CYP19A1CYP11B1CYP11B2CYP3A4ALDH1A1 | |
| SCHEMBL6540845 | 0.73 | CYP11B1 (0.54) | CYP19A1CYP11B1CYP11B2CYP3A4ALDH1A1 | |
| SCHEMBL29205321 | 0.73 | ALDH1A1 (0.54) | CYP19A1CYP11B1CYP11B2FGFR1CYP3A4 | |
| SCHEMBL6224414 | 0.72 | ALDH1A1 (0.58) | FGFR1ALDH1A1LMNATSHRTDP1 | |
| SCHEMBL1239793 | 0.71 | ALDH1A1 (0.59) | CYP19A1CYP11B1CYP11B2CYP3A4ALDH1A1 | |
| SCHEMBL28418568 | 0.71 | IDO1 (0.58) | CYP19A1CYP11B1CYP11B2CYP3A4ALDH1A1 | |
| SCHEMBL1239502 | 0.70 | CYP11B1 (0.56) | CYP19A1CYP11B1CYP11B2CYP3A4ALDH1A1 | |
| SCHEMBL27677862 | 0.70 | TLR2 (0.46) | CYP19A1CYP11B1CYP11B2CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104529809-B | A kind of preparation method of polysubstituted imidazole derivative | 浙江大学 | 2016-08-24 | — | — | CN | disclosed |