Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.46 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.46 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7039417 | 0.84 | ALDH1A1 (0.51) | MAPK1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL1995690 | 0.82 | ALDH1A1 (0.56) | MAPK1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL29398386 | 0.82 | ALDH1A1 (0.56) | MAPK1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL28832945 | 0.80 | TSHR (0.55) | MAPK1ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL1264392 | 0.78 | MAPK1 (0.46) | MAPK1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL1264694 | 0.78 | MAPK1 (0.46) | MAPK1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL28840504 | 0.78 | ALDH1A1 (0.56) | MAPK1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL1264388 | 0.75 | MAPT (0.46) | MAPK1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL29942185 | 0.75 | ALDH1A1 (0.60) | MAPK1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL7240751 | 0.75 | ALDH1A1 (0.60) | MAPK1ALDH1A1CYP3A4HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187915-A | There is inhibitor of ALK Yu EGFR double activity and its preparation method and application | 上海翰森生物医药科技有限公司 | 2016-12-07 | — | — | CN | disclosed |