Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 5/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.69 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.69 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.62 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.55 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 6/20 | 0.52 |
| ▸ | PPARD | Q03181 | 6/20 | 0.52 |
| ▸ | PPARA | Q07869 | 6/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL27410652 | 0.97 | LMNA (0.69) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL27661128 | 0.97 | LMNA (0.69) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Glutarate SCHEMBL27542711 | 0.93 | SLC22A6 (0.73) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL28114194 | 0.91 | GPR84 (0.62) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Formic Acid SCHEMBL5931486 | 0.89 | GPR84 (0.75) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL28187590 | 0.89 | LMNA (0.58) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Hexanoate SCHEMBL27603848 | 0.87 | AKR1B1 (0.80) | LMNATSHRSLC22A6GPR84FFAR1 | |
| Succinic Acid SCHEMBL6699563 | 0.86 | LMNA (0.69) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL8941691 | 0.86 | LMNA (1.00) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL1330953 | 0.86 | LMNA (1.00) | LMNATSHRNFKB1PMP22SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105860126-A | Process for producing foam mouldings | 辛布拉技术有限公司 | 2016-08-17 | — | — | CN | claimed |
| CN-110423184-A | A kind of solid propellant rocket propellant and preparation method thereof | SHANGHAI AVIATION CHEMICAL APPLICATION RES INSTITUTE | 2019-11-08 | — | — | CN | disclosed |
| CN-106751615-B | A kind of high dispersive, biodegradable Masterbatch of low water absorption and preparation method thereof | 广东波斯科技股份有限公司 | 2019-07-26 | — | — | CN | disclosed |
| CN-106751615-A | A kind of high dispersive, biodegradable Masterbatch of low water absorption and preparation method thereof | 广东波斯科技股份有限公司 | 2017-05-31 | — | — | CN | disclosed |
| CN-106032093-A | Stationery from environmentally friendly materials and resins | 尚图·帕特尔 | 2016-10-19 | — | — | CN | disclosed |