SCHEMBL28091175

SCHEMBL28091175

CCCNc1cc(CC)ccc1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.53
IDO1 P14902 1/20 0.50
ADRA2A P08913 2/20 0.41
ADRA2B P18089 2/20 0.41
ADRA2C P18825 2/20 0.41
ADRA1A P35348 2/20 0.41
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
POLB P06746 2/20 0.39
MAPT P10636 5/20 0.38
ALOX15 P16050 3/20 0.38
HSD17B10 Q99714 3/20 0.38
MAPK1 P28482 2/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38
TSHR P16473 1/20 0.38
NFKB1 P19838 1/20 0.38
THPO P40225 1/20 0.38
HIF1A Q16665 1/20 0.38
CA12 O43570 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29069494 0.88 TRPA1 (0.48) TRPA1MAPTHSD17B10MEN1KMT2A
SCHEMBL28091170 0.79 IDO1 (0.51) TRPA1IDO1POLBMAPTALOX15
SCHEMBL13754317 0.79 TRPA1 (0.59) TRPA1IDO1ADRA2AADRA2BADRA2C
SCHEMBL27139926 0.78 IDO1 (0.50) IDO1ALOX15HSD17B10MAPK1TSHR
SCHEMBL10873964 0.77 ALDH1A1 (0.57) TRPA1IDO1POLBMAPTALOX15
SCHEMBL23432543 0.76 IDO1 (0.53) IDO1ADRA2AADRA2BADRA2CADRA1A
SCHEMBL1955931 0.76 IDO1 (0.61) IDO1MAPTALOX15HSD17B10MAPK1
SCHEMBL7529112 0.75 PTGS2 (0.44) POLBMAPTMAPK1TSHRCA2
SCHEMBL10922812 0.75 KDM5A (0.44) TRPA1ADRA2AADRA2BADRA2CADRA1A
SCHEMBL28091172 0.74 TRPA1 (0.53) TRPA1IDO1ADRA2AADRA2BADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105802610-B Fluorine ion fluorescent probe and application 中国科学院理化技术研究所 2018-05-04 CN disclosed
CN-105802610-A Fluorine ion fluorescent probe and application 中国科学院理化技术研究所 2016-07-27 CN disclosed