Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 5/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28091661 | 0.79 | MEN1 (0.41) | MEN1KMT2AUSP2TDP1MAPT | |
| SCHEMBL25178380 | 0.75 | MAPT (0.48) | MEN1KMT2AUSP2TDP1MAPT | |
| SCHEMBL27692151 | 0.73 | SHMT2 (0.45) | MEN1KMT2AUSP2TDP1MAPT | |
| SCHEMBL28203288 | 0.72 | MEN1 (0.38) | MEN1KMT2AUSP2TDP1MAPT | |
| SCHEMBL27555197 | 0.71 | MEN1 (0.56) | MEN1KMT2AUSP2TDP1MAPT | |
| SCHEMBL28774867 | 0.70 | MEN1 (0.36) | MEN1KMT2AUSP2TDP1MAPT | |
| SCHEMBL29051504 | 0.69 | PTGS1 (0.41) | MEN1KMT2AMAPTALDH1A1FFAR1 | |
| SCHEMBL27778006 | 0.69 | EGFR (0.55) | MEN1KMT2AUSP2TDP1MAPT | |
| SCHEMBL27712024 | 0.68 | MEN1 (0.37) | MEN1KMT2AUSP2TDP1MAPT | |
| SCHEMBL18334435 | 0.66 | GAA (0.55) | MEN1KMT2ATDP1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980363-A | Aminopyrazolone Derivatives | 第三共株式会社 | 2016-09-28 | — | — | CN | disclosed |