Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25178380 | 0.80 | MAPT (0.48) | MEN1KMT2AATMMAPTSMN1; SMN2 | |
| SCHEMBL28774867 | 0.78 | MEN1 (0.36) | MEN1KMT2AATMMAPTHSP90AA1 | |
| SCHEMBL11068412 | 0.74 | MEN1 (0.54) | MEN1KMT2AATMMAPTHSP90AA1 | |
| SCHEMBL7721905 | 0.74 | L3MBTL1 (0.40) | MEN1KMT2ASIGMAR1ATMMAPT | |
| SCHEMBL16139718 | 0.74 | MEN1 (0.36) | MEN1KMT2ASIGMAR1ATMMAPT | |
| SCHEMBL7717975 | 0.73 | ALDH1A1 (0.39) | MEN1KMT2ASIGMAR1ATMMAPT | |
| SCHEMBL7714597 | 0.71 | DPP4 (0.37) | MEN1KMT2AATMMAPTSMN1; SMN2 | |
| SCHEMBL7719090 | 0.70 | PRKCZ (0.35) | MEN1KMT2ASIGMAR1ATMMAPT | |
| SCHEMBL1781467 | 0.70 | NOS1 (0.39) | MEN1KMT2ASIGMAR1ATMMAPT | |
| SCHEMBL11060055 | 0.68 | EGFR (0.53) | MEN1KMT2AATMMAPTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112375072-B | Pyrazolone derivative, injection and application thereof | 上海长征富民金山制药有限公司 | 2021-05-28 | — | — | CN | claimed |
| CN-112375072-A | Pyrazolone derivative, injection and application thereof | 上海长征富民金山制药有限公司 | 2021-02-19 | — | — | CN | claimed |
| CN-107796889-B | Method for derivatization and separation analysis of amino pyrazolone iso-bifunctional reagent for reducing sugar chain and glycoprotein O-sugar chain | 西北大学 | 2020-04-10 | — | — | CN | claimed |
| CN-107796889-A | The different two functional group reagents derivatization of amino-pyrazol quinoline ketone and method for separating and analyzing of reproducibility sugar chain and glycoprotein O sugar chains | 西北大学 | 2018-03-13 | — | — | CN | claimed |
| CN-112375072-B | Pyrazolone derivative, injection and application thereof | 上海长征富民金山制药有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-112375072-A | Pyrazolone derivative, injection and application thereof | 上海长征富民金山制药有限公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-107796889-B | Method for derivatization and separation analysis of amino pyrazolone iso-bifunctional reagent for reducing sugar chain and glycoprotein O-sugar chain | 西北大学 | 2020-04-10 | — | — | CN | disclosed |
| CN-107796889-A | The different two functional group reagents derivatization of amino-pyrazol quinoline ketone and method for separating and analyzing of reproducibility sugar chain and glycoprotein O sugar chains | 西北大学 | 2018-03-13 | — | — | CN | disclosed |