Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | NPY1R | P25929 | 1/20 | 0.61 |
| ▸ | MC4R | P32245 | 1/20 | 0.61 |
| ▸ | NPY2R | P49146 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026664 | 0.81 | MAPT (0.67) | MAPTLMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL1454743 | 0.81 | MAPT (0.70) | MAPTLMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL13401489 | 0.80 | ALDH1A1 (0.72) | MAPTLMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL11305819 | 0.79 | MAPT (0.73) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL12316880 | 0.78 | MAPT (0.69) | MAPTLMNAALDH1A1HTTKMT2A | |
| SCHEMBL1454119 | 0.78 | KMT2A (0.73) | MAPTLMNAALDH1A1HTTPKM | |
| SCHEMBL1455286 | 0.78 | KMT2A (0.90) | MAPTLMNAALDH1A1HTTMEN1 | |
| SCHEMBL8305318 | 0.78 | MAPT (0.57) | MAPTLMNAALDH1A1HTTMEN1 | |
| SCHEMBL8303930 | 0.78 | POLB (0.57) | MAPTLMNAALDH1A1HTTMEN1 | |
| SCHEMBL7161319 | 0.78 | CRHBP (0.77) | MAPTLMNAL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111269157-B | Amisulpride impurity and preparation method thereof | 南京海纳医药科技股份有限公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-111269157-A | Amisulpride impurity and preparation method thereof | 南京海纳医药科技股份有限公司 | 2020-06-12 | — | — | CN | disclosed |
| CN-105936625-A | Synthesis method of 3-amino-4-chloro-N-(3-chloro-2-methylphenyl)benzamide | 常州市阿曼特化工有限公司 | 2016-09-14 | — | — | CN | disclosed |