Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 3/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6081390 | 0.87 | TRPM8 (0.64) | HTR1DTRPM8KDM4EMAPTLTA4H | |
| Ethoxycarbonyl Group SCHEMBL27581538 | 0.87 | HTR1D (0.52) | HTR1DTRPM8KDM4EMAPTLTA4H | |
| SCHEMBL27725148 | 0.83 | TRPM8 (0.53) | HTR1DTRPM8KDM4EMAPTLTA4H | |
| Tert-Butyl Formate SCHEMBL27613248 | 0.81 | ACHE (0.43) | HTR1DTRPM8KDM4EMAPTLTA4H | |
| SCHEMBL12293240 | 0.78 | TRPM8 (0.60) | HTR1DTRPM8KDM4EMAPTLTA4H | |
| Tert-Butyl Formate SCHEMBL27752473 | 0.78 | NSD2 (0.48) | HTR1DKDM4EMAPTMEN1KMT2A | |
| SCHEMBL29055668 | 0.77 | HTR1D (0.54) | HTR1DTRPM8KDM4EMAPTLTA4H | |
| SCHEMBL23089216 | 0.77 | IMPDH2 (0.65) | HTR1DTRPM8KDM4EMAPTLTA4H | |
| SCHEMBL29814579 | 0.77 | IMPDH2 (0.65) | HTR1DTRPM8KDM4EMAPTLTA4H | |
| Tert-Butyl Formate SCHEMBL27895342 | 0.76 | CYP2A6 (0.45) | KDM4EMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008466-A | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | 艾伯维公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-102307622-B | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维公司 | 2016-08-17 | — | — | CN | disclosed |