Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | LTA4H | P09960 | 4/20 | 0.62 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.62 |
| ▸ | HTR1D | P28221 | 5/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.56 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | HTR1B | P28222 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29814579 | 0.88 | IMPDH2 (0.65) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| SCHEMBL23089216 | 0.88 | IMPDH2 (0.65) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| Tert-Butyl Formate SCHEMBL28092121 | 0.87 | HTR1D (0.51) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| Ethoxycarbonyl Group SCHEMBL27581538 | 0.87 | HTR1D (0.52) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| SCHEMBL29055668 | 0.86 | HTR1D (0.54) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| SCHEMBL29007183 | 0.82 | TRPM8 (0.76) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| SCHEMBL29617411 | 0.82 | TRPM8 (0.76) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| SCHEMBL2004881 | 0.82 | TRPM8 (0.64) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| SCHEMBL28506218 | 0.82 | TRPM8 (0.64) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| SCHEMBL8654866 | 0.82 | TRPM8 (0.60) | TRPM8KDM4EMAPTLTA4HPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2023-08-17 | — | — | US | disclosed |
| US-20060004428-A1 | Pyrrolo (3,4-c) carbazole and pyrido (2,3-b) pyrrolo (3,4-e) indole derivatives, preparation method and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2006-01-05 | — | — | US | disclosed |
| CN-1705667-A | New fused pyrrolo-carbazole or pyrido-pyrrolo-indole derivatives (i), useful for treating cancer | SERVIER LAB (FR) | 2005-12-07 | — | — | CN | disclosed |
| EP-1554277-A1 | PYRROLO (3,4-C) CARBAZOLE AND PYRIDO (2,3-B) PYRROLO (3,4-E) INDOLE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004035582-A1 | PYRROLO (3,4-C) CARBAZOLE AND PYRIDO (2,3-B) PYRROLO (3,4-E) INDOLE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2004-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | DNPEP, BCAT1, ANPEP | TRPM8 4519/4885KDM4E 4463/4885MAPT 1129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.