Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 2/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699184 | 0.98 | LMNA (0.51) | LMNAL3MBTL1MAPTCRHR1ELANE | |
| SCHEMBL30827899 | 0.98 | LMNA (0.51) | LMNAL3MBTL1MAPTCRHR1ELANE | |
| SCHEMBL1577814 | 0.85 | LMNA (0.67) | LMNAL3MBTL1MAPTCRHR1ELANE | |
| SCHEMBL318514 | 0.83 | MAPT (0.64) | LMNAL3MBTL1MAPTCRHR1KDM4E | |
| SCHEMBL9494309 | 0.81 | LMNA (0.43) | LMNAL3MBTL1MAPTCRHR1ELANE | |
| SCHEMBL14690812 | 0.80 | NR4A2 (0.50) | LMNAL3MBTL1MAPTCRHR1PARP1 | |
| SCHEMBL18197787 | 0.80 | NR4A2 (0.47) | LMNAL3MBTL1MAPTCRHR1ELANE | |
| SCHEMBL20304317 | 0.80 | L3MBTL1 (0.44) | LMNAL3MBTL1MAPTCRHR1ELANE | |
| SCHEMBL28280276 | 0.80 | LMNA (0.49) | LMNAL3MBTL1MAPTELANEPARP1 | |
| SCHEMBL2711191 | 0.77 | ELANE (0.48) | LMNAL3MBTL1MAPTCRHR1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105829294-A | METHYLENE LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T | 詹森药业有限公司 | 2016-08-03 | — | — | CN | disclosed |