Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.44 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.42 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.42 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2949235 | 0.85 | DAO (0.45) | KCNQ3KCNQ2KCNQ4KCNQ5CYP3A4 | |
| SCHEMBL17634090 | 0.85 | PPARD (0.43) | LMNAKCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL3587496 | 0.85 | KCNQ3 (0.50) | LMNAALDH1A1NPC1RAB9ASYK | |
| SCHEMBL3963929 | 0.82 | TRPV4 (0.44) | KCNQ3KCNQ2KCNQ4KCNQ5CYP3A4 | |
| SCHEMBL263863 | 0.80 | GABRP (0.56) | SMN1; SMN2PPARDPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL30025563 | 0.80 | GABRP (0.56) | SMN1; SMN2PPARDPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL2310832 | 0.79 | MAOB (0.46) | KCNQ3KCNQ2KCNQ4KCNQ5MRGPRX4 | |
| SCHEMBL20425110 | 0.79 | RAB9A (0.51) | LMNAALDH1A1NPC1RAB9ACYP4F2 | |
| SCHEMBL30394818 | 0.79 | MAOB (0.46) | KCNQ3KCNQ2KCNQ4KCNQ5MRGPRX4 | |
| SCHEMBL24973127 | 0.78 | CYP2C9 (0.43) | KCNQ3KCNQ2KCNQ4KCNQ5CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105829294-B | The quinolyl conditioning agent of ROR- γ-T being connect with methylene | 詹森药业有限公司 | 2018-11-09 | — | — | CN | disclosed |
| CN-104854087-B | Indole carboxamide derivatives as P2X receptor antagonists | 埃科特莱茵药品有限公司 | 2017-03-22 | — | — | CN | disclosed |
| CN-105829294-A | METHYLENE LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T | 詹森药业有限公司 | 2016-08-03 | — | — | CN | disclosed |