Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 3/20 | 0.43 |
| ▸ | TKT | P29401 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.41 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.39 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.39 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.39 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30025563 | 0.84 | GABRP (0.56) | TRPV4DAOPPARDMRGPRX4PLAAT3 | |
| SCHEMBL263863 | 0.84 | GABRP (0.56) | TRPV4DAOPPARDMRGPRX4PLAAT3 | |
| SCHEMBL12479488 | 0.84 | TRPV4 (0.46) | TRPV4DAOTKTCYP3A4CYP3A5 | |
| SCHEMBL12091528 | 0.84 | CCR9 (0.42) | PPARDCYP2C19TRPV1GABRPGABRD | |
| SCHEMBL15087614 | 0.83 | DAO (0.48) | TRPV4DAOTKTCYP3A4CYP3A5 | |
| SCHEMBL17634090 | 0.83 | PPARD (0.43) | TRPV4DAOTKTCYP3A4CYP3A5 | |
| SCHEMBL2310832 | 0.83 | MAOB (0.46) | TRPV4DAOKCNQ3KCNQ2KCNQ4 | |
| SCHEMBL30394818 | 0.83 | MAOB (0.46) | TRPV4DAOKCNQ3KCNQ2KCNQ4 | |
| SCHEMBL24973127 | 0.82 | CYP2C9 (0.43) | TRPV4DAOTKTCYP3A4CYP3A5 | |
| SCHEMBL28093133 | 0.82 | LMNA (0.49) | TRPV4DAOCYP3A4CYP3A5PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3784669-B1 | PTERIDINONE COMPOUNDS AND USES THEREOF | VERTEX PHARMA (US) | 2023-10-25 | — | — | EP | disclosed |
| US-11737463-B2 | Pyridine and pyrazine compounds | BASF SE (DE) | 2023-08-29 | — | — | US | disclosed |
| US-20110071289-A1 | AMINOPYRAZOLE AMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2011-03-24 | — | — | US | disclosed |
| WO-2009035855-A2 | NOVEL USES OF HALOGENATED ALKYL SULFONAMIDES | H. LUNDBECK A/S (DK) | 2009-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11737463-B2 | Pyridine and pyrazine compounds | NDUFS5, IL5, NDUFS4 | TRPV4 1760/4885DAO 2627/4885TKT 952/4885 |
| US-20110071289-A1 | AMINOPYRAZOLE AMIDE DERIVATIVE | ARGLU1, ARG1, CNKSR1 | TRPV4 4792/4885DAO 414/4885TKT 3840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.