Acrylamide

Acrylamide

SCHEMBL28093276

C=C(C)C(=O)OCCCC1(C)CC[Si](C)(C)[Si](C)(C)O1.C=CC(N)=O

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL216519 0.92 TSHR (0.41) TSHRTHRB
SCHEMBL10535303 0.80 TSHR (0.37) TSHRTHRB
SCHEMBL704975 0.78 TSHR (0.42) TSHRTHRB
SCHEMBL1046022 0.77 ALDH1A1 (0.37) TSHRTHRB
SCHEMBL5028823 0.76 TSHR (0.40) TSHRTHRB
SCHEMBL22733939 0.75 TSHR (0.41) TSHRTHRB
SCHEMBL27847987 0.72 TSHR (0.49) TSHRTHRB
SCHEMBL1317456 0.72 TSHR (0.51) TSHRTHRB
SCHEMBL712919 0.70 TSHR (0.43) TSHRTHRB
SCHEMBL7936332 0.69 TSHR (0.40) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105980124-A Improved method for manufacturing silicone hydrogel contact lenses 诺华股份有限公司 2016-09-28 CN claimed
CN-106715101-B Method for applying a stable coating on a silicone hydrogel contact lens 诺华股份有限公司 2019-11-05 CN disclosed
CN-105579480-B Method for making UV absorbing ophthalmic lenses 诺华股份有限公司 2019-02-22 CN disclosed
CN-105334640-B Silicone hydrogel lenses with rich water surface 诺华股份有限公司 2018-12-28 CN disclosed
CN-108367517-A Method for producing the haptic lens with lubricated surface 诺华股份有限公司 2018-08-03 CN disclosed
CN-107532038-A For producing the method in the haptic lens thereon with durable lubricant coating 诺华股份有限公司 2018-01-02 CN disclosed
CN-106896422-A Silicone hydrogel lens with nano-textured surface 诺华股份有限公司 2017-06-27 CN disclosed
CN-106715101-A Method for applying a stable coating on a silicone hydrogel contact lens 诺华股份有限公司 2017-05-24 CN disclosed
CN-103597378-B Silicone hydrogel lenses with nanotextured surfaces 诺瓦提斯公司 2017-02-15 CN disclosed
CN-105980124-A Improved method for manufacturing silicone hydrogel contact lenses 诺华股份有限公司 2016-09-28 CN disclosed