Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125010 | 0.96 | TSHR (0.45) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL8356186 | 0.86 | TSHR (0.42) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL2441414 | 0.83 | TSHR (0.34) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL2580886 | 0.74 | THRB (0.40) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL27798588 | 0.72 | TSHR (0.54) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL23070781 | 0.69 | — | — | |
| SCHEMBL1318275 | 0.68 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL10577843 | 0.66 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL1356956 | 0.66 | TSHR (0.46) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL321925 | 0.65 | TSHR (0.85) | TSHRHPGDALDH1A1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024406-B1 | A SILICONE ACRYLATE HYBRID COMPOSITION | DOW CORNING (US) | 2012-08-01 | — | — | EP | claimed |
| US-20090196911-A1 | Silicone Acrylate Hybride Composition and Method Of Making Same | DOW SILICONES CORPORATION | 2009-08-06 | — | — | US | claimed |
| EP-2024406-A2 | A SILICONE ACRYLATE HYBRID COMPOSITION | DOW CORNING CORPORATION (US) | 2009-02-18 | — | — | EP | claimed |
| EP-1940368-A2 | TRANSDERMAL DRUG DELIVERY SYSTEM WITH ACRYLATE OR METHACRYLATE FUNCTIONAL PRESSURE SENSITIVE ADHESIVE COMPOSITION | DOW CORNING CORPORATION (US) | 2008-07-09 | — | — | EP | claimed |
| WO-2007145996-A9 | A SILICONE ACRYLATE HYBRID COMPOSITION | DOW CORNING (US) | 2008-02-14 | — | — | WO | claimed |
| WO-2007145996-A2 | A SILICONE ACRYLATE HYBRID COMPOSITION | DOW CORNING CORPORATION (US) | 2007-12-21 | — | — | WO | claimed |
| WO-2007050580-A2 | TRANSDERMAL DRUG DELIVERY SYSTEM WITH ACRYLATE OR METHACRYLATE FUNCTIONAL PRESSURE SENSITIVE ADHESIVE COMPOSITION | DOW CORNING CORPORATION (US) | 2007-05-03 | — | — | WO | claimed |
| EP-3256504-B1 | MULTI-PHASE SILICONE ACRYLIC HYBRID VISCO-ELASTIC COMPOSITIONS AND METHODS OF MAKING SAME | DOW SILICONES CORP (US) | 2020-06-24 | — | — | EP | disclosed |
| US-10316228-B2 | Multi-phase silicone acrylic hybrid visco-elastic compositions and methods of making same | DOW SILICONES CORPORATION (US) | 2019-06-11 | — | — | US | disclosed |
| US-9946158-B2 | Composition for forming resist underlayer film for nanoimprint | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2018-04-17 | — | — | US | disclosed |
| EP-2461350-B1 | USE OF A COMPOSITION FOR FORMING RESIST UNDERLAYER FILM FOR NANOIMPRINT LITHOGRAPHY | NISSAN CHEMICAL IND LTD (JP) | 2018-02-28 | — | — | EP | disclosed |
| US-20180002583-A1 | MULTI-PHASE SILICONE ACRYLIC HYBRID VISCO-ELASTIC COMPOSITIONS AND METHODS OF MAKING SAME | DOW SILICONES CORPORATION | 2018-01-04 | — | — | US | disclosed |
| EP-3256504-A1 | MULTI-PHASE SILICONE ACRYLIC HYBRID VISCO-ELASTIC COMPOSITIONS AND METHODS OF MAKING SAME | Dow Corning Corporation (US) | 2017-12-20 | — | — | EP | disclosed |
| US-8048615-B2 | Silicon-containing resist underlayer coating forming composition for forming photo-crosslinking cured resist underlayer coating | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-11-01 | — | — | US | disclosed |
| US-20090196911-A1 | Silicone Acrylate Hybride Composition and Method Of Making Same | DOW SILICONES CORPORATION | 2009-08-06 | — | — | US | disclosed |
| US-20090162782-A1 | Silicon-Containing Resist Underlayer Coating Forming Composition for Forming Photo-Crosslinking Cured Resist Underlayer Coating | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-06-25 | — | — | US | disclosed |
| EP-2024406-A2 | A SILICONE ACRYLATE HYBRID COMPOSITION | DOW CORNING CORPORATION (US) | 2009-02-18 | — | — | EP | disclosed |
| EP-1972998-A1 | SILICON-CONTAINING RESIST UNDERLYING LAYER FILM FORMING COMPOSITION FOR FORMATION OF PHOTOCROSSLINKING CURED RESIST UNDERLYING LAYER FILM | Nissan Chemical Industries, Ltd. (JP) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007145996-A9 | A SILICONE ACRYLATE HYBRID COMPOSITION | DOW CORNING (US) | 2008-02-14 | — | — | WO | disclosed |
| WO-2007145996-A2 | A SILICONE ACRYLATE HYBRID COMPOSITION | DOW CORNING CORPORATION (US) | 2007-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090196911-A1 | Silicone Acrylate Hybride Composition and Method Of Making Same | MMS19, CAD, ACR | TSHR 4760/4885HPGD 1051/4885ALDH1A1 2679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.