Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | LAP3 | P28838 | 3/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL381461 | 0.84 | FDPS (0.45) | FDPSGGPS1LAP3ANPEP | |
| SCHEMBL9633056 | 0.83 | GGPS1 (0.41) | FDPSGGPS1 | |
| SCHEMBL2807785 | 0.80 | HMGCR (0.48) | GGPS1TRPA1 | |
| SCHEMBL9633047 | 0.79 | FDPS (0.42) | FDPSGGPS1LAP3ANPEPPTPRC | |
| SCHEMBL9632077 | 0.76 | GGPS1 (0.47) | GGPS1 | |
| SCHEMBL9632066 | 0.76 | GGPS1 (0.47) | GGPS1 | |
| SCHEMBL9638742 | 0.74 | FDPS (0.50) | FDPSLAP3ANPEP | |
| SCHEMBL17748389 | 0.73 | TRPA1 (0.44) | GGPS1TRPA1 | |
| SCHEMBL21074632 | 0.72 | FDPS (0.49) | FDPSLAP3ANPEP | |
| SCHEMBL743405 | 0.72 | FDPS (0.50) | FDPSLAP3ANPEPPTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240612-A1 | Prenylated Bisphosphonates as Anti-tuberculosis Agents | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2010-09-23 | — | — | US | disclosed |
| US-20100240612-A1 | Prenylated Bisphosphonates as Anti-tuberculosis Agents | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240612-A1 | Prenylated Bisphosphonates as Anti-tuberculosis Agents | GGPS1, FDPS, DCTPP1 | FDPS 2/4885GGPS1 1/4885TRPA1 3730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.