Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.31 |
| ▸ | G6PD | P11413 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27589264 | 0.86 | MAPK1 (0.43) | MAPK1SLC18A3GAAGFERALOX5 | |
| Tert-Butyl Formate SCHEMBL28044015 | 0.77 | TDP1 (0.41) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28780380 | 0.77 | GPR119 (0.42) | MAPK1GPR119TDP1ALDH1A1 | |
| SCHEMBL1358636 | 0.71 | GAA (0.40) | MAPK1GAAALDH1A1ADAMTS5 | |
| SCHEMBL27493040 | 0.70 | L3MBTL1 (0.41) | MAPK1SLC18A3GAAALOX5ALDH1A1 | |
| Tert-Butyl Formate SCHEMBL28313000 | 0.69 | TRIM24 (0.46) | MAPK1GPR119TDP1GAAALDH1A1 | |
| Tert-Butyl Formate SCHEMBL28307746 | 0.69 | SIGMAR1 (0.47) | — | |
| Tert-Butyl Formate SCHEMBL27801242 | 0.68 | ALDH1A1 (0.47) | MAPK1GPR119TDP1GFERALDH1A1 | |
| SCHEMBL27990003 | 0.67 | GAA (0.39) | TDP1GAAGFERALOX5ALDH1A1 | |
| Tert-Butyl Formate SCHEMBL28750430 | 0.67 | TDP1 (0.50) | TDP1ALDH1A1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105934246-B | Tetrahydroquinoline compositions as BET bromodomain inhibitors | 福马疗法公司 | 2019-10-22 | — | — | CN | disclosed |
| CN-105934246-A | Tetrahydroquinoline compositions as BET bromodomain inhibitors | 福马疗法公司 | 2016-09-07 | — | — | CN | disclosed |