Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | DHODH | Q02127 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5134325 | 0.75 | CA12 (0.43) | KMT2AMEN1DHODHKDM4EALDH1A1 | |
| SCHEMBL5703391 | 0.71 | PDE10A (0.58) | KMT2AMEN1DHODHKDM4EPDE10A | |
| SCHEMBL4012935 | 0.71 | SMN1; SMN2 (0.54) | KMT2AMEN1DHODHKDM4EPDE10A | |
| SCHEMBL38662586 | 0.70 | MEN1 (0.71) | KMT2AMEN1KDM4EPDE10ATSHR | |
| SCHEMBL2443270 | 0.70 | MEN1 (0.71) | KMT2AMEN1KDM4EPDE10ATSHR | |
| SCHEMBL6584881 | 0.70 | KDM4E (0.56) | KMT2AMEN1KDM4EPDE10ASMN1; SMN2 | |
| SCHEMBL4012934 | 0.69 | KMT2A (0.54) | KMT2AMEN1KDM4EPDE10ATSHR | |
| Hydrochloric Acid SCHEMBL7531424 | 0.69 | KDM4E (0.54) | KMT2AMEN1KDM4EPDE10ASMN1; SMN2 | |
| SCHEMBL7104600 | 0.69 | MEN1 (0.57) | KMT2AMEN1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL641899 | 0.68 | PDE10A (0.66) | KMT2AMEN1DHODHKDM4EPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101918367-B | Acridine compounds Facile N-alkylation in ionic liquid | 西门子医疗保健诊断公司 | 2016-08-24 | — | — | CN | disclosed |