Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27833492 | 1.00 | ALDH1A1 (0.48) | ALDH1A1KMT2ASMN1; SMN2DPP4PARP15 | |
| SCHEMBL28946375 | 0.90 | HCRTR1 (0.46) | KMT2AMAOAMAOBHCRTR1HCRTR2 | |
| SCHEMBL27904166 | 0.83 | ALDH1A1 (0.40) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL27796088 | 0.80 | PARP10 (0.47) | PARP15PARP10PARP2CHEK2MAOA | |
| SCHEMBL27655729 | 0.80 | ALDH1A1 (0.34) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL28277464 | 0.80 | KMT2A (0.38) | ALDH1A1KMT2ASMN1; SMN2PARP10CHEK2 | |
| SCHEMBL27655719 | 0.76 | ALDH1A1 (0.34) | ALDH1A1DPP4 | |
| SCHEMBL27757343 | 0.76 | ALDH1A1 (0.34) | ALDH1A1DPP4 | |
| SCHEMBL28798303 | 0.76 | SIGMAR1 (0.46) | KMT2A | |
| SCHEMBL28760362 | 0.76 | SSTR4 (0.45) | ALDH1A1KMT2ASMN1; SMN2PARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608449-A | Compound as type III receptor tyrosine kinase inhibitors | 阵列生物制药公司 | 2019-04-12 | — | — | CN | disclosed |
| CN-105924437-B | Compound as type III receptor tyrosine kinase inhibitors | 阵列生物制药公司 | 2018-11-30 | — | — | CN | disclosed |
| CN-105924437-A | Compounds As Type III Receptor Tyrosine Kinase Inhibitors | 阵列生物制药公司 | 2016-09-07 | — | — | CN | disclosed |