Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28095478 | 0.90 | ALDH1A1 (0.48) | HCRTR1HCRTR2KMT2AMAOAMAOB | |
| SCHEMBL27833492 | 0.90 | ALDH1A1 (0.48) | HCRTR1HCRTR2KMT2AMAOAMAOB | |
| SCHEMBL28798303 | 0.87 | SIGMAR1 (0.46) | KMT2A | |
| SCHEMBL1769253 | 0.80 | CHEK2 (0.56) | HCRTR1HCRTR2KMT2A | |
| SCHEMBL27796088 | 0.79 | PARP10 (0.47) | MAOAMAOB | |
| SCHEMBL28129909 | 0.79 | SCN9A (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL27655729 | 0.79 | ALDH1A1 (0.34) | KMT2A | |
| SCHEMBL27751590 | 0.78 | RBP4 (0.43) | KMT2A | |
| SCHEMBL7953492 | 0.76 | MAOA (0.53) | HCRTR1HCRTR2DRD2DRD4MAOA | |
| SCHEMBL3326084 | 0.76 | HCRTR1 (0.39) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102656158-B | Novel heterocyclic acrylamides and their use as pharmaceuticals | FAB PHARMA SAS | 2015-02-11 | — | — | CN | disclosed |
| CN-102656158-A | Novel heterocyclic acrylamides and their use as pharmaceuticals | FAB PHARMA SAS | 2012-09-05 | — | — | CN | disclosed |