Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28095648

CCCCOS(=O)c1ccc(C(F)(F)F)cc1.N

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.36
ALOX5 P09917 4/20 0.36
PPARG P37231 4/20 0.36
PTGES O14684 3/20 0.36
CYP1A1 P04798 1/20 0.36
CYP1B1 Q16678 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
LMNA P02545 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PPARA Q07869 3/20 0.34
PPARD Q03181 2/20 0.34
PSEN1 P49768 3/20 0.34
ATP4A P20648 2/20 0.34
ATP4B P51164 2/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
HDAC3 O15379 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6744587 0.78 RECQL (0.47) ALOX5PPARGPTGESMEN1KMT2A
SCHEMBL6002555 0.76 TSHR (0.46) LMNASMN1; SMN2
SCHEMBL6745076 0.73 RECQL (0.46) LMNAHTTSMN1; SMN2
SCHEMBL12067142 0.72 CES2 (0.39) CA1CA2CA9
SCHEMBL12409185 0.72 CHRNB2 (0.54) CYP1A1CYP1B1PPARAATP4AATP4B
Butylamine SCHEMBL28095649 0.72 TAAR1 (0.40) MEN1KMT2ALMNAHTTSMN1; SMN2
SCHEMBL6002444 0.71 TSHR (0.47) MEN1KMT2ALMNASMN1; SMN2
Tetrabuthylammonium SCHEMBL1826223 0.71 MEN1 (0.38) MEN1KMT2ALMNAHTTSMN1; SMN2
SCHEMBL8915435 0.70 TSHR (0.49) PPARGMEN1KMT2ALMNASMN1; SMN2
SCHEMBL20526214 0.70 TSHR (0.49) PPARGMEN1KMT2ALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104781218-B Polymerisable spirobiindene monomer and polymer prepared therefrom 3M创新有限公司 2016-10-26 CN disclosed