Butylamine

Butylamine

SCHEMBL28095649

CCCCN.O=S(O)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.40
LMNA P02545 5/20 0.38
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
HTT P42858 1/20 0.38
CYP1A2 P05177 3/20 0.36
CYP3A4 P08684 3/20 0.36
CYP2C19 P33261 3/20 0.36
SLC6A4 P31645 3/20 0.36
CYP2D6 P10635 2/20 0.36
CYP2C9 P11712 2/20 0.36
HIF1A Q16665 2/20 0.36
NFKB1 P19838 1/20 0.36
SLC6A2 P23975 1/20 0.36
ADRA1A P35348 1/20 0.36
OPRK1 P41145 1/20 0.36
SLC6A3 Q01959 1/20 0.36
KCNH2 Q12809 1/20 0.36
SCN5A Q14524 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrabuthylammonium SCHEMBL1826223 0.83 MEN1 (0.38) LMNAMEN1KMT2ASMN1; SMN2HTT
SCHEMBL1827236 0.81 CES2 (0.48) CYP1A2ALDH1A1CES2CES1
Butylamine SCHEMBL19834169 0.80 ALDH1A1 (0.44) TAAR1LMNASMN1; SMN2CYP1A2CYP3A4
SCHEMBL3300798 0.79 CES2 (0.46) CYP1A2ALDH1A1CES2CES1
SCHEMBL30097988 0.79 CES2 (0.46) CYP1A2ALDH1A1CES2CES1
SCHEMBL1583590 0.79 CES2 (0.46) CYP1A2ALDH1A1CES2CES1
Butylamine SCHEMBL19834144 0.79 GABBR2 (0.39) TAAR1LMNAMEN1KMT2ASMN1; SMN2
Butylamine SCHEMBL31036023 0.79 ALDH1A1 (0.43) TAAR1LMNASMN1; SMN2CYP1A2CYP3A4
Butylamine SCHEMBL3152634 0.78 SMN1; SMN2 (0.41) SMN1; SMN2CES2CES1
Ammonia Solution, Strong SCHEMBL28095648 0.72 PTGDR2 (0.36) LMNAMEN1KMT2ASMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104781218-B Polymerisable spirobiindene monomer and polymer prepared therefrom 3M创新有限公司 2016-10-26 CN disclosed