Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28096112 | 0.88 | SLC6A3 (0.39) | ALOX5POLBLMNATP53THRB | |
| SCHEMBL27482821 | 0.78 | POLB (0.45) | PKMALOX5POLBLMNATP53 | |
| SCHEMBL29290745 | 0.77 | POLB (0.47) | PKMPOLBMEN1USP2KMT2A | |
| SCHEMBL27476954 | 0.75 | POLB (0.43) | PKMALOX5POLBMEN1KMT2A | |
| SCHEMBL5325399 | 0.74 | HTR2A (0.42) | LMNATP53HTTTSHRMAPT | |
| SCHEMBL3908791 | 0.74 | TSHR (0.42) | PKMPOLBNPC1RAB9ACES2 | |
| SCHEMBL29290741 | 0.74 | CYP2C19 (0.51) | PKMALOX5POLBLMNANPSR1 | |
| SCHEMBL7279728 | 0.74 | KCNA5 (0.44) | PKMPOLBKMT2ANPC1RAB9A | |
| SCHEMBL11903248 | 0.72 | ALOX5 (0.46) | PKMALOX5POLBLMNATP53 | |
| SCHEMBL15572492 | 0.72 | PKM (0.57) | PKMPOLBLMNAMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105924425-A | Preparation method of dihydrothiochroman derivative | 浙江师范大学 | 2016-09-07 | — | — | CN | disclosed |