Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TNF | P01375 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10289141 | 0.86 | MAPT (0.49) | HSD17B10MAPK1ALDH1A1KDM4ETSHR | |
| SCHEMBL789757 | 0.85 | GAA (0.58) | HSD17B10ALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL14305917 | 0.84 | GAA (0.57) | HSD17B10ALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL9954016 | 0.82 | TSHR (0.50) | HSD17B10ALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL9955070 | 0.76 | GAA (0.41) | HSD17B10ALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL9954790 | 0.75 | SHMT2 (0.41) | HSD17B10ALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL2402633 | 0.72 | ALDH1A1 (0.70) | ALDH1A1KDM4ETSHRKMT2ACYP2D6 | |
| SCHEMBL6200528 | 0.72 | KMT2A (0.83) | HSD17B10MAPK1ALDH1A1KDM4ETSHR | |
| SCHEMBL2379664 | 0.72 | ALDH1A1 (0.62) | HSD17B10MAPK1ALDH1A1KDM4ETSHR | |
| SCHEMBL6447545 | 0.71 | ALDH1A1 (0.64) | ALDH1A1TSHRKMT2ACYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104011045-B | Dihydrobenzoxazine and dihydropyridinooxazine derivatives | 诺华股份有限公司 | 2016-08-24 | — | — | CN | disclosed |