Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | FASN | P49327 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27936500 | 0.88 | FASN (0.43) | USP30ARFASNHSD11B1GPR119 | |
| Hydrochloric Acid SCHEMBL28007552 | 0.86 | FASN (0.42) | USP30ARFASNHSD11B1GPR119 | |
| SCHEMBL28024239 | 0.81 | BRD4 (0.42) | ALDH1A1 | |
| SCHEMBL27979570 | 0.81 | SLC18A3 (0.33) | ALDH1A1 | |
| SCHEMBL28103918 | 0.80 | USP30 (0.41) | USP30ALDH1A1 | |
| SCHEMBL28822639 | 0.80 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL28834474 | 0.80 | ACACB (0.46) | ALDH1A1 | |
| SCHEMBL15601524 | 0.78 | GPR119 (0.54) | USP30ARFASNGPR119 | |
| SCHEMBL27679915 | 0.77 | ALDH1A1 (0.37) | ARALDH1A1GPR119 | |
| SCHEMBL27699801 | 0.77 | MAPT (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061963-B | Heterocyclic modulators of lipid synthesis and combinations thereof | 3-V生物科学股份有限公司 | 2019-10-22 | — | — | CN | disclosed |
| CN-106061963-A | Heterocyclic modulators of lipid synthesis and combinations thereof | 3-V生物科学股份有限公司 | 2016-10-26 | — | — | CN | disclosed |