Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.32 |
| ▸ | ABAT | P80404 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28014692 | 0.89 | NAMPT (0.40) | ALDH1A1NAMPTCYP2C9RIPK1MAPT | |
| SCHEMBL27979570 | 0.84 | SLC18A3 (0.33) | ALDH1A1NAMPTLMNACYP2C9TSHR | |
| SCHEMBL28024239 | 0.84 | BRD4 (0.42) | ALDH1A1LMNACYP2C9MAPT | |
| SCHEMBL28103918 | 0.82 | USP30 (0.41) | ALDH1A1LMNATSHRMAPT | |
| SCHEMBL28096231 | 0.80 | USP30 (0.43) | ALDH1A1 | |
| SCHEMBL28834474 | 0.79 | ACACB (0.46) | ALDH1A1MAPTKDM4EPARP10 | |
| SCHEMBL27699801 | 0.79 | MAPT (0.42) | ALDH1A1LMNAMAPT | |
| SCHEMBL570438 | 0.78 | RORC (0.45) | NAMPTKDM4E | |
| SCHEMBL28044694 | 0.77 | CA12 (0.44) | ALDH1A1LMNACYP2C9TSHRMAPT | |
| SCHEMBL28675131 | 0.75 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103270036-B | As antiparasitic isoxazoline derivative | ZOETIS LLC (US) | 2015-11-25 | — | — | CN | disclosed |