Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | CHUK | O15111 | 1/20 | 0.45 |
| ▸ | IKBKG | Q9Y6K9 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290238 | 0.83 | SMN1; SMN2 (0.56) | CNR1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL2787018 | 0.81 | SMN1; SMN2 (0.41) | HTR2CIKBKBALDH1A1MAPTNPC1 | |
| SCHEMBL2809700 | 0.78 | HTR2C (0.56) | HTR2CCNR1THRATHRBCES2 | |
| SCHEMBL288852 | 0.78 | KDM4E (0.59) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL289905 | 0.77 | HPGD (0.60) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL12789540 | 0.75 | CNR1 (0.77) | HTR2CCNR1THRATHRBCES2 | |
| SCHEMBL289881 | 0.75 | SMN1; SMN2 (0.61) | CNR1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL290307 | 0.74 | CD274 (0.61) | IKBKBCHUKIKBKGALDH1A1MAPT | |
| SCHEMBL3828069 | 0.74 | LMNA (0.51) | IKBKBALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL290239 | 0.72 | CYP2A6 (0.42) | IKBKBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |