Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28097128

Cc1ccc(S(=O)(=O)n2ccnc2)cc1.N

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.67
TSHR P16473 1/20 0.67
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
L3MBTL1 Q9Y468 2/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
ALDH1A1 P00352 2/20 0.50
HTT P42858 2/20 0.48
LMNA P02545 1/20 0.45
CYP19A1 P11511 2/20 0.45
FABP4 P15090 1/20 0.44
PKM P14618 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL217862 0.98 TP53 (0.69) TP53TSHRCA1CA2L3MBTL1
SCHEMBL28102124 0.81 TP53 (0.64) TP53TSHRCA1CA2ALDH1A1
SCHEMBL4728733 0.80 TP53 (0.63) TP53TSHRL3MBTL1MEN1KMT2A
SCHEMBL31024013 0.77 TP53 (0.59) TP53TSHRCA1CA2KMT2A
SCHEMBL14273105 0.76 CA1 (0.62) CA1CA2L3MBTL1MEN1KMT2A
SCHEMBL10801457 0.76 SMN1; SMN2 (0.65) TP53TSHRL3MBTL1MEN1KMT2A
SCHEMBL5670454 0.75 TP53 (0.44) TP53TSHRCA1CA2L3MBTL1
SCHEMBL288347 0.75 FKBP1A (0.49) TP53TSHRCA1CA2L3MBTL1
SCHEMBL27676576 0.74 TP53 (0.63) TP53TSHRCA1CA2L3MBTL1
SCHEMBL14216332 0.74 CA1 (0.47) TP53TSHRCA1CA2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105968051-A Organic small molecular fluorescent probe for detecting methanol and preparation method of organic small molecular fluorescent probe 天津大学 2016-09-28 CN claimed
CN-105968051-A Organic small molecular fluorescent probe for detecting methanol and preparation method of organic small molecular fluorescent probe 天津大学 2016-09-28 CN disclosed