SCHEMBL217862

SCHEMBL217862

Cc1ccc(S(=O)(=O)n2ccnc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.69
TSHR P16473 1/20 0.69
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
L3MBTL1 Q9Y468 2/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
ALDH1A1 P00352 2/20 0.51
HTT P42858 2/20 0.49
LMNA P02545 1/20 0.46
CYP19A1 P11511 1/20 0.46
FABP4 P15090 1/20 0.45
PKM P14618 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28097128 0.98 TP53 (0.67) TP53TSHRCA1CA2L3MBTL1
SCHEMBL28102124 0.82 TP53 (0.64) TP53TSHRCA1CA2ALDH1A1
SCHEMBL4728733 0.81 TP53 (0.63) TP53TSHRL3MBTL1MEN1KMT2A
SCHEMBL31024013 0.78 TP53 (0.59) TP53TSHRCA1CA2KMT2A
SCHEMBL14273105 0.77 CA1 (0.62) CA1CA2L3MBTL1MEN1KMT2A
SCHEMBL10801457 0.77 SMN1; SMN2 (0.65) TP53TSHRL3MBTL1MEN1KMT2A
SCHEMBL288347 0.76 FKBP1A (0.49) TP53TSHRCA1CA2L3MBTL1
SCHEMBL27676576 0.76 TP53 (0.63) TP53TSHRCA1CA2L3MBTL1
SCHEMBL14216332 0.76 CA1 (0.47) TP53TSHRCA1CA2L3MBTL1
SCHEMBL1364805 0.75 CA1 (1.00) CA1CA2L3MBTL1ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 618 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12194448-B2 Catalysts for the transformation of carbon dioxide and glycerol to formic acid and lactic acid and methods of making the same THE GEORGE WASHINGTON UNIVERSITY (US) 2025-01-14 US claimed
CN-117317221-A High-first-efficiency high-power hard carbon negative electrode material and preparation method thereof 安徽天宏基科技有限公司 2023-12-29 CN claimed
CN-116396587-A In-situ aluminum nitride frame/polymer composite material and preparation method thereof 海南大学 2023-07-07 CN claimed
CN-116355353-A Silicon nitride whisker reinforced silicon carbide/polymer composite material and preparation method thereof 海南大学 2023-06-30 CN claimed
CN-116355354-A Silicon carbide frame/polymer composite material and preparation method thereof 海南大学 2023-06-30 CN claimed
CN-115418149-A Non-asphalt-based non-cured waterproof coating and preparation method thereof 北京东方雨虹防水技术股份有限公司 2022-12-02 CN claimed
CN-111548356-B Process for preparing tert-butyl-1, 8-dioxa-4, 11-diazaspiro [5.6] dodecane-11-carboxylic acid ester 无锡合全药业有限公司 2022-05-17 CN claimed
CN-109942762-B Preparation method of surface treating agent with flame retardant property 上海普信高分子材料有限公司 2021-10-22 CN claimed
CN-112961375-A Chitosan-based self-repairing hydrogel and preparation method thereof 广东工业大学 2021-06-15 CN claimed
CN-112280272-A High-molecular packaging material and preparation method thereof 程朝刚 2021-01-29 CN claimed
WO-2002099023-A2 ENZYMATIC SYSTEMS FOR GENERATING ACTIVE OXYGEN SPECIES FOR REACTING WITH OTHER PRECURSORS TO OBTAIN OXIDATION AND/OR BLEACHING CALL, KRIMHILD (DE) 2002-12-12 WO claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0251760-B1 Rubber composition BRIDGESTONE CORP (JP) 1994-01-26 EP claimed
US-5140055-A Improved high speed grip performance BRIDGESTONE CORPORATION (JP) 1992-08-18 US claimed
EP-0061760-B1 A METHOD FOR PREPARING A MONONUCLEOTIDE-3'-PHOSPHODIESTER-BASED SUBSTRATE Baker Instruments Corporation (US) 1988-03-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12194448-B2 Catalysts for the transformation of carbon dioxide and glycerol to formic acid and lactic acid and methods of making the same MLX, LDHA, CA2 TP53 2528/4885TSHR 2120/4885CA1 13/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.