Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 4/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL217862 | 0.82 | TP53 (0.69) | TP53TSHRALDH1A1LMNAFABP4 | |
| SCHEMBL4728733 | 0.81 | TP53 (0.63) | TP53TSHRALDH1A1LMNAFABP4 | |
| Ammonia Solution, Strong SCHEMBL28097128 | 0.81 | TP53 (0.67) | TP53TSHRALDH1A1LMNAFABP4 | |
| SCHEMBL31024013 | 0.78 | TP53 (0.59) | TP53TSHRALDH1A1CA12CA1 | |
| SCHEMBL27676576 | 0.72 | TP53 (0.63) | TP53TSHRALDH1A1LMNAFABP4 | |
| SCHEMBL23086183 | 0.71 | LMNA (0.45) | TSHRALDH1A1LMNAMAPTMMP2 | |
| SCHEMBL27781439 | 0.71 | LMNA (0.42) | TSHRALDH1A1LMNAMAPTHTR6 | |
| SCHEMBL21804937 | 0.68 | TSHR (0.55) | TP53TSHRALDH1A1LMNAHTT | |
| SCHEMBL14529331 | 0.68 | HTT (0.52) | TP53TSHRALDH1A1LMNAFABP4 | |
| SCHEMBL22558824 | 0.68 | CA2 (0.58) | TP53TSHRALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008360-A | Sulfanilyl imidazole and preparation method thereof | 华南农业大学 | 2016-10-12 | — | — | CN | claimed |
| CN-106008360-B | A kind of sulfanilyl imidazoles and preparation method thereof | 华南农业大学 | 2018-10-16 | — | — | CN | disclosed |
| CN-106008360-B | A kind of sulfanilyl imidazoles and preparation method thereof | 华南农业大学 | 2018-10-16 | — | — | CN | disclosed |
| CN-106008360-B | A kind of sulfanilyl imidazoles and preparation method thereof | 华南农业大学 | 2018-10-16 | — | — | CN | disclosed |
| CN-106008360-A | Sulfanilyl imidazole and preparation method thereof | 华南农业大学 | 2016-10-12 | — | — | CN | disclosed |
| CN-106008360-A | Sulfanilyl imidazole and preparation method thereof | 华南农业大学 | 2016-10-12 | — | — | CN | disclosed |