Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11349063 | 0.75 | CHRNB2 (0.60) | NPC1RAB9AALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL11340243 | 0.74 | ALDH1A1 (0.44) | NPC1RAB9AALDH1A1SMN1; SMN2PAX8 | |
| SCHEMBL4354144 | 0.73 | RORC (0.53) | RORCNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL27754507 | 0.73 | PTGIR (0.51) | NPC1RAB9AALDH1A1HTTKMT2A | |
| SCHEMBL8370314 | 0.70 | NPC1 (0.55) | NPC1RAB9AALDH1A1SMN1; SMN2PAX8 | |
| SCHEMBL11546490 | 0.68 | TSHR (0.50) | NPC1RAB9AALDH1A1SMN1; SMN2PAX8 | |
| SCHEMBL11430998 | 0.68 | TSHR (0.50) | NPC1RAB9AALDH1A1SMN1; SMN2PAX8 | |
| SCHEMBL16681003 | 0.68 | ATM (0.41) | ALDH1A1KMT2AMEN1TDP1HDAC1 | |
| SCHEMBL4921591 | 0.67 | TSHR (0.49) | NPC1RAB9AALDH1A1SMN1; SMN2PAX8 | |
| SCHEMBL6717574 | 0.67 | TSHR (0.49) | NPC1RAB9AALDH1A1SMN1; SMN2PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105873925-B | Antiparasitic and insecticidal isoxazoline compounds | 勃林格殷格翰动物保健美国公司 | 2019-09-10 | — | — | CN | disclosed |
| CN-105873925-A | Antiparasitic and insecticidal isoxazoline compounds | 梅里亚股份有限公司 | 2016-08-17 | — | — | CN | disclosed |