Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.41 |
| ▸ | MLYCD | O95822 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10893930 | 0.83 | RORC (0.46) | RORCSMN1; SMN2CYP3A4ALDH1A1TSHR | |
| SCHEMBL26128801 | 0.81 | SMN1; SMN2 (0.49) | RORCMEN1KMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL3644869 | 0.80 | MEN1 (0.45) | RORCMEN1KMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL2511559 | 0.78 | ALDH1A1 (0.50) | RORCMEN1KMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL17165741 | 0.78 | ALDH1A1 (0.48) | RORCMEN1KMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL13735234 | 0.77 | ALDH1A1 (0.52) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL20681717 | 0.77 | RORC (0.60) | RORCMEN1KMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL9160381 | 0.76 | ALDH1A1 (0.56) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| Fluoride SCHEMBL10887965 | 0.75 | ALDH1A1 (0.50) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL4732176 | 0.74 | ALDH1A1 (0.54) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10093683-B2 | Factor XIa inhibitors | MERCK SHARP & DOHME CORP. (US) | 2018-10-09 | — | — | US | disclosed |
| US-20170044183-A1 | FACTOR XIa INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2017-02-16 | — | — | US | disclosed |
| US-9475762-B2 | Process for the preparation of urethanes | COVESTRO DEUTSCHLAND AG (DE) | 2016-10-25 | — | — | US | disclosed |
| US-20160152559-A1 | PROCESS FOR THE PREPARATION OF URETHANES | COVESTRO DEUTSCHLAND AG (DE) | 2016-06-02 | — | — | US | disclosed |
| US-9284267-B2 | Process for the preparation of urethanes | BAYER MATERIALSCIENCE AG (DE) | 2016-03-15 | — | — | US | disclosed |
| CN-101932555-B | Process for preparing carbamates | BAYER MATERIALSCIENCE AG | 2014-03-19 | — | — | CN | disclosed |
| EP-2497082-B1 | Fluorurethane as additive in a photopolymer formulation | BAYER IP GMBH (DE) | 2013-09-04 | — | — | EP | disclosed |
| US-20090275771-A1 | Process for the preparation of urethanes | COVESTRO DEUTSCHLAND AG (DE) | 2009-11-05 | — | — | US | disclosed |
| WO-2009095164-A1 | METHOD FOR PRODUCING URETHANES | BAYER MATERIALSCIENCE AG (DE) | 2009-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160152559-A1 | PROCESS FOR THE PREPARATION OF URETHANES | OGG1, SOD1, DUOX2 | RORC 2913/4885MEN1 3634/4885KMT2A 674/4885 |
| US-20170044183-A1 | FACTOR XIa INHIBITORS | F11, SERPINC1, TFPI | RORC 4537/4885MEN1 641/4885KMT2A 1209/4885 |
| US-10093683-B2 | Factor XIa inhibitors | F11, F12, SERPINC1 | RORC 4726/4885MEN1 475/4885KMT2A 1422/4885 |
| US-20090275771-A1 | Process for the preparation of urethanes | OGG1, SOD1, DUOX2 | RORC 2913/4885MEN1 3634/4885KMT2A 674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.