Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7064540 | 0.90 | RAB9A (0.56) | RAB9AALDH1A1RXRARXRBSMN1; SMN2 | |
| SCHEMBL4594651 | 0.85 | ELANE (0.56) | RAB9AALDH1A1RXRARXRBSMN1; SMN2 | |
| SCHEMBL68678 | 0.83 | LMNA (0.59) | RAB9AALDH1A1RXRARXRBSMN1; SMN2 | |
| SCHEMBL7061682 | 0.82 | RAB9A (0.54) | RAB9AALDH1A1RXRARXRBSMN1; SMN2 | |
| SCHEMBL11783023 | 0.82 | LMNA (0.57) | RAB9AALDH1A1RXRARXRBSMN1; SMN2 | |
| SCHEMBL47952 | 0.81 | RAB9A (0.56) | RAB9AALDH1A1RXRARXRBSMN1; SMN2 | |
| SCHEMBL7064280 | 0.81 | RAB9A (0.49) | RAB9AALDH1A1RXRARXRBSMN1; SMN2 | |
| SCHEMBL16192677 | 0.80 | ELANE (0.51) | RAB9AALDH1A1RXRARXRBSMN1; SMN2 | |
| SCHEMBL28097757 | 0.79 | RAB9A (0.47) | RAB9AALDH1A1RXRARXRBSMN1; SMN2 | |
| SCHEMBL9577301 | 0.79 | PTGS2 (0.52) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104379251-B | Use of certain metal accumulating plants for carrying out organic chemical reactions | 国家科研中心 | 2017-07-21 | — | — | CN | disclosed |
| US-20160237023-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES | UNIVERSITÄT ZU KÖLN (DE) | 2016-08-18 | — | — | US | disclosed |
| CN-104379251-A | Use of certain metal accumulating plants for carrying out organic chemical reactions | CENTRE NAT RECH SCIENT | 2015-02-25 | — | — | CN | disclosed |
| EP-0407588-B1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEM RES (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5028738-A | Process for producing 2-oxo-3-aromatic carboxylic acid derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0407588-A1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-16 | — | — | EP | disclosed |
| EP-0009642-B1 | PREPARATION OF PHOSPHAZENE COPOLYMERS CONTAINING UNSATURATED SUBSTITUENTS DERIVED FROM PYRUVATE ESTERS AND ALDEHYDES OR KETONES | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1982-03-24 | — | — | EP | disclosed |
| US-4221904-A | Polyphosphazene copolymers containing substituents derived from pyruvate esters | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1980-09-09 | — | — | US | disclosed |
| EP-0009642-A1 | Preparation of phosphazene copolymers containing unsaturated substituents derived from pyruvate esters and aldehydes or ketones | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1980-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160237023-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES | APC, BRCA1, VHL | RAB9A 2267/4885ALDH1A1 434/4885RXRA 264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.