SCHEMBL28097878

SCHEMBL28097878

NCc1ccc(C(F)(c2ccc(CN)c(N)c2)C(F)(F)C(F)(F)F)cc1N

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
AOC1 P19801 2/20 0.32
AOC3 Q16853 2/20 0.32
ALDH1A1 P00352 2/20 0.32
PKM P14618 1/20 0.32
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28230962 0.81 ESR1 (0.38) AOC1AOC3ALDH1A1PKMKDM4E
SCHEMBL31472982 0.81 ALDH1A1 (0.47) ALDH1A1PKMKDM4EHPGDHSD17B10
SCHEMBL4590973 0.81 ALDH1A1 (0.47) ALDH1A1PKMKDM4EHPGDHSD17B10
SCHEMBL20920802 0.79 ALDH1A1 (0.38) ALDH1A1PKMKDM4EHPGDHSD17B10
SCHEMBL27721574 0.79 NR1H2 (0.41) ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL25211449 0.74 ALDH1A1 (0.37) ALDH1A1PKMKDM4EHPGDHSD17B10
SCHEMBL5145634 0.74 ALDH1A1 (0.43) ALDH1A1PKMKDM4EHPGDHSD17B10
SCHEMBL272276 0.74 ALDH1A1 (0.55) ALDH1A1PKMKDM4EHPGDHSD17B10
SCHEMBL18392736 0.73 ALDH1A1 (0.53) AOC1AOC3ALDH1A1PKMHPGD
SCHEMBL28230312 0.71 LOXL2 (0.44) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110147031-A The manufacturing method and display device of photosensitive polymer combination, heat-resistant resin film 东丽株式会社 2019-08-20 CN disclosed
CN-108027562-B Minus photosensitive composition, cured film, element and display device 东丽株式会社 2019-07-05 CN disclosed
CN-109843534-A The manufacturing method of optical film 柯尼卡美能达株式会社 2019-06-04 CN disclosed
CN-109804306-A Light orientation copolymer material 罗利克技术有限公司 2019-05-24 CN disclosed
CN-104854508-B The manufacturing method and display device of photosensitive polymer combination, heat-resistant resin film 东丽株式会社 2019-05-07 CN disclosed
CN-109348718-A Polyimide resin, uses its touch panel and its manufacturing method, colour filter and its manufacturing method, liquid crystal cell and its manufacturing method, organic EL element and its manufacturing method at polyimide resin composition 东丽株式会社 2019-02-15 CN disclosed
CN-108912011-A Light arrangement material 罗立克科技股份公司 2018-11-30 CN disclosed
CN-108884245-A Polyimide film and method for producing same 柯尼卡美能达株式会社 2018-11-23 CN disclosed
CN-108885920-A Resin composition 三菱化学株式会社 2018-11-23 CN disclosed
CN-106873249-B Light alignment materials with side draw generation 罗利克有限公司 2018-09-14 CN disclosed
CN-108473698-A Manufacturing method, Kapton, polyamic acid solution and the photosensitive composite of Kapton JXTG能源株式会社 2018-08-31 CN disclosed
CN-108473677-A Polyamide acid composition with improved adhesive strength and polyimide film comprising same 株式会社斗山 2018-08-31 CN disclosed
CN-108431088-A Polyamide acid solution using diamine monomer having novel structure and polyimide film comprising same 株式会社斗山 2018-08-21 CN disclosed
CN-108350174-A Photo-alignment material 罗利克技术有限公司 2018-07-31 CN disclosed
CN-108350363-A Can photo-alignment material composition 罗利克技术有限公司 2018-07-31 CN disclosed
CN-104854193-B Compositions, aligning agent for liquid crystal, liquid crystal orientation film and liquid crystal display cells 日产化学工业株式会社 2016-11-09 CN disclosed