Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25595752 | 0.89 | CHRNB2 (0.50) | GAACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL28284116 | 0.82 | CHRM2 (0.37) | CHRM2ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL27645900 | 0.81 | CYP2C9 (0.37) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL17670555 | 0.79 | EPHX1 (0.40) | EPHX1ACHE | |
| SCHEMBL11100479 | 0.79 | EPHX1 (0.52) | ALDH1A1TSHRATMSMN1; SMN2EPHX1 | |
| SCHEMBL17393935 | 0.79 | ACHE (0.44) | EPHX1ACHE | |
| SCHEMBL15211959 | 0.79 | EPHX1 (0.57) | GAACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL29148821 | 0.77 | EPHX1 (0.37) | EPHX1ACHE | |
| SCHEMBL21059108 | 0.77 | EPHX1 (0.60) | EPHX1ACHE | |
| SCHEMBL12057397 | 0.77 | EPHX1 (0.37) | GAAEPHX1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103936716-B | Tool muscarinic receptor antagonists and the diamide compound of beta 2 adrenoreceptor agonists activity | 施万呼吸有限责任公司 | 2016-09-07 | — | — | CN | disclosed |