Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25595752 | 0.84 | CHRNB2 (0.50) | CYP2C19CHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL28758495 | 0.84 | PAOX (0.36) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL28137724 | 0.81 | KDM4E (0.37) | KDM4EALDH1A1SMN1; SMN2MAPTACHE | |
| SCHEMBL28098386 | 0.81 | GAA (0.41) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL27872670 | 0.80 | ACHE (0.38) | CHRNB2CHRNA4CHRNB4CHRNA3ACHE | |
| SCHEMBL28860189 | 0.79 | CA12 (0.36) | CYP2C9CYP2C19KDM4EALDH1A1PAOX | |
| SCHEMBL28995266 | 0.75 | CYP2C19 (0.47) | CYP2C9CYP2C19ANPEPCHRNB2CHRNA4 | |
| SCHEMBL13283862 | 0.75 | CYP2C9 (0.42) | CYP2C9CYP2C19ANPEPCHRNB2CHRNA4 | |
| SCHEMBL27766308 | 0.74 | ACHE (0.35) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL28244485 | 0.74 | GAA (0.37) | KDM4EALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1917873-A | Diurea derivatives | ACTIVE BIOTECH AB (SE) | 2007-02-21 | — | — | CN | disclosed |