Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | RXRG | P48443 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.39 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.39 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2280232 | 0.87 | AKR1C2 (0.47) | GPBAR1RXRARXRBRXRGNR4A2 | |
| SCHEMBL4243317 | 0.72 | GRM5 (0.41) | — | |
| SCHEMBL6771333 | 0.72 | MAPK13 (0.47) | GPBAR1 | |
| SCHEMBL27753405 | 0.71 | ACMSD (0.50) | IP6K1IP6K3IP6K2ALDH1A1KMO | |
| SCHEMBL11395576 | 0.70 | JAK2 (0.55) | L3MBTL1KDM4EALDH1A1HTTHPGD | |
| SCHEMBL27830585 | 0.70 | RXRA (0.41) | RXRARXRBRXRGIP6K1IP6K3 | |
| SCHEMBL6267437 | 0.70 | PTGS2 (0.58) | ALDH1A1NPC1RAB9ATSHRSMN1; SMN2 | |
| SCHEMBL6260456 | 0.69 | PTGS2 (0.56) | L3MBTL1KDM4EALDH1A1HTTNPC1 | |
| SCHEMBL2468990 | 0.68 | PTGS2 (0.45) | GPBAR1RXRARXRBRXRGNR4A2 | |
| SCHEMBL7794331 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104194386-B | A kind of fluorescence increases red and preparation method thereof | 上海东升新材料有限公司 | 2016-09-28 | — | — | CN | disclosed |