Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 4/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28133754 | 0.82 | PDE4A (0.44) | NR1H2NR1H3ADORA1HSD17B1HSD17B2 | |
| SCHEMBL4150417 | 0.72 | RAB9A (0.52) | HSD17B1HSD17B2ATMTDP1L3MBTL1 | |
| SCHEMBL1505897 | 0.72 | TTR (0.53) | NR1H2NR1H3ADORA1ATMTDP1 | |
| SCHEMBL8769335 | 0.72 | AKR1C3 (0.48) | HSD17B1HSD17B2ATMTDP1L3MBTL1 | |
| SCHEMBL5502719 | 0.70 | BCAT2 (0.41) | ALDH1A1PTPN22PTPRCPTPN9PTPN11 | |
| SCHEMBL934810 | 0.69 | AKR1C3 (0.59) | NR1H2NR1H3ADORA1ATMTDP1 | |
| SCHEMBL10647658 | 0.69 | BCL2 (0.53) | HSD17B1HSD17B2ATMTDP1L3MBTL1 | |
| SCHEMBL15793447 | 0.68 | MAPT (0.50) | ADORA1ATMTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL10644840 | 0.68 | HPGD (0.48) | ATMTDP1L3MBTL1PDE4AHPGD | |
| SCHEMBL7557427 | 0.68 | AKR1C3 (0.48) | ATMTDP1L3MBTL1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105940036-A | POLYMERIC MATERIALS | 威格斯制造有限公司 | 2016-09-14 | — | — | CN | disclosed |